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A submitted PMTA is not FDA marketing authorization or approval.

The US is included in the grey line for 'western European and other countries' The above shows the proportion of students in 12th, 10th and 8th grades who used vapes containing nicotine annually since 2019 Over the same period, four countries have gone the other way and lifted their restrictions on vapes Egypt, Kuwait, Bahrain and the Palestinian territories

Enrollees in the gradual-quit group did get to choose whether, in the two-week period over which they were to stop smoking, they would taper their daily cigarettes, observe smoke-free periods, or smoke on a schedule

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The research was supported by funding from the National Institute on Drug Abuse (K08/MSN276344) and the Wisconsin Department of Health Services (AWD00003494).