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Intriguingly, while VRK2 wild-type tumors were resistant to APR-017 monotherapy, combinatorial treatment with the VRK2 inhibitor IC261 restored their sensitivity to APR-017 (Fig

[Article] [PubMed]113

HTY can neutralize reactive oxygen species through hydrogen atom transfer (HAT) mechanisms, in which phenolic hydroxyl groups donate hydrogen atoms to peroxyl radicals, leading to the formation of relatively stable phenoxy radicals that interrupt radical chain reactions [3, 4]

How to Use: At the moisturiser step of the skincare routine, apply an adequate layer and smooth it to allow absorption