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Lab Invest 80 , 735744 (2000)

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In mammalian nervous systems, many different types of chemical substances, including amino acids (e.g., glutamate), monoamines (e.g., dopamine, norepinephrine), acetylcholine, peptides (e.g., substance P), serve as neurotransmitters to bind their corresponding receptors, then activate ion channels, and consequently produce ion flux 1 , thereby inducing membrane potential changes that lead to signal propagation for neurotransmission 1,2,3,4

No contexto de pesquisa de novos agentes teraputicos, eles so estudados por seus potenciais efeitos na composio corporal e na recuperao tecidual