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These medications can help people lose weight by reducing appetite, increasing feelings of fullness, and improving blood sugar control

In cardiovascular outcome trials of semaglutide in type 2 diabetes, rapid improvements in glycemic control were associated with an increased rate of diabetic retinopathy complications in high-risk patients, likely reflecting the well-known phenomenon of transient retinopathy worsening when glucose control improves quickly.9 More recently, observational analyses and pharmacovigilance reports have raised a possible association between semaglutide exposure and nonarteritic anterior ischemic optic neuropathy (NAION), leading to ongoing regulatory review

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Vitamin B 12 is not a substitute for folic acid and since it might improve folic acid deficient megaloblastic anemia, indiscriminate use of vitamin B 12 could mask the true diagnosis