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This makes them useful to manage type 2 diabetes and obesity

Common side effects include nausea, vomiting, and diarrhoea, particularly during dose escalation

Rarely, immune-related inflammation of the kidneys (acute interstitial nephritis) has been reported

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According to Mankin et al, the rigorousness of the OA destruction was categorized using the histologic standards (Table 2) based on structural variations (scale range 06), cellular variations (scale range 03), damage of safranin O staining (scale range 04) and tidemark integrity (scale range 01) by 3 independent researchers