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Vitamin C and glutathione are potent antioxidants that are intricately linked biochemically

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For instance, in HeLa cells, glutathione redox potentials are more reducing in the mitochondrial matrix than in the cytoplasm (Couto et al., 2016), whereas the activity of glutathione transferases can differ between cellular compartments, including cytosol, mitochondria, and nucleus (Raza, 2011)

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