Rosati A, Poliani PL, Todeschini A, Cominelli M, Medicina D, Cenzato M, Simoncini EL, Magrini SM, Buglione M, Grisanti S, Padovani A
[Google Scholar] Chronic inflammation and mutagenesis
The GREAT study will evaluate the characteristics of the enrolled population, HAE attack rate (on treatment with garadacimab vs pre-enrolment baseline), time to occurrence of first HAE attack, the proportion of patients achieving attack-free status and attack-free duration
The KIT gene controls mast cell creation from stem cells in the bone marrow, and mutations in KIT cause excess mast cell proliferation.[ref][ref] A mastocytosis diagnosis is either systemic mastocytosis (affecting the whole body) or cutaneous mastocytosis, which has more skin-related symptoms
Thats why its important to discuss any existing prescriptions with a health care provider before beginning treatment