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By beginning at a small dose, the body is able to gradually adjust, which reduces the side effects

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Data availability Data sharing is not applicable to this article as no datasets were generated or analyzed during the current study

Emerging research including new guidance from the InfantRisk Center suggests that the biggest concern during breastfeeding may not be medication transfer into breast milk , but whether the parent is able to consume enough calories and nutrients to support milk production

treatment of DIO mice with either vehicle, acyl-GIP 13,14,15 (150 nmol kg 1 ), acyl-GLP-1 (50 nmol kg 1 ) 13,14,15 , the acylated peptide GIPR antagonist (1,500 nmol kg 1 ) 22 or the GIPR:GLP-1R co-agonist MAR709 (50 nmol kg 1 ) 13,14,15 (Fig