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Since the BBB also prevents most small-molecule drugs in addition to the previously mentioned viral vectors from being able to enter the CNS, the recent development of AAV9 variants have been a potential key in solving this issue

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Operational Roadblocks as You Grow Spreadsheets and sticky notes might work for a handful of patients

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212 Disruption of Mg 2+ homeostasis within mitochondria not only impacts the morphology and dynamics of mitochondria but also disturbs ATP synthesis and energy metabolism