doi:10.1016/j.envres.2021.111028
Conventionally, the selective vulnerability of neuronal populations to disease processes is usually attributed to their inherent properties (i.e., high metabolic rate, ROS generation, and extensive arborisation with increased energy demand) [133,136,137]
The lipotoxic effects of lipid accumulation include disturbances in metabolism, oxidative stress, mitochondrial dysfunction, proinflammatory signaling and accumulation of lipid derivatives like diacyloglycerol and ceramide [81]
found MTHFR polymorphisms to be insignificant in the incidence of PTB [159]
As individuals complete these programs, the focus shifts to sustaining weight loss and health through long-term metabolic resets and the development of healthy habits, ultimately paving the way for a healthier future for Californians