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RothCLPerezFAWhitlockKBElfersCYanovskiJAShoemakerAHet alA phase 3 randomized clinical trial using a once-weekly glucagon-like peptide-1 receptor agonist in adolescents and young adults with hypothalamic obesity

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NAC directly replenishes intracellular glutathione, restoring feedback inhibition on the gamma-glutamyl cycle and reducing 5-oxoproline accumulation [6]