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Animal studies show comparable efficacy from 10 ng/kg to 10 mg/kg, spanning a 1000-fold range

When neurotrophic signaling systems such as BDNF are well supported, neural circuits may maintain stronger connectivity and adaptability, supporting memory, learning, and mood stability

It was suggested that the differentiated production of IL-1 and IL-8 may be linked to the type of product applied, either an irritant or a sensitizer 39,40

In one study, one-third to two-thirds of the weight lost using lifestyle interventions was regained within 1 year following the end of treatment, and greater than 95% of the weight was regained within 5 years

References: Davies MJ, Bajaj HS, Broholm C, et al