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Benefits of IGF-1 LR3 6.1 Muscle Growth and Repair Accelerates regeneration of damaged muscle fibers Enhances hypertrophy when paired with resistance training Supports recovery from injury 6.2 Fat Metabolism Increases lean body mass while reducing fat mass Promotes greater caloric expenditure at rest 6.3 Connective Tissue and Joint Health Stimulates collagen synthesis in tendons and ligaments Supports rehabilitation from overuse injuries 6.4 Bone Density Support Promotes osteoblast activity and bone remodeling May help counteract osteoporosis risk 6.5 Anti-Aging Potential Supports maintenance of muscle mass with age Enhances repair mechanisms in multiple tissues 7

Research has focused on deeper sleep, lean mass, and recovery, particularly in adults 35 and older

These include Lactobacillus rhamnosus GG, Lacticaseibacillus casei , Bifidobacterium longum , as well as next-generation taxa such as Akkermansia muciniphila and Faecalibacterium prausnitzii

Jee et al., 2025)