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Affects roughly 1 in 200 people of Northern European descent

Published in Diabetologia (Blher and colleagues, NCT04153929), this Phase 2 trial randomized 413 adults with type 2 diabetes on background metformin to survodutide across several once-weekly or twice-weekly dose groups, to placebo, or to open-label semaglutide up to 1.0 mg once weekly

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However, glutathione is not a readily available substance that can be mass-produced cheaply

This method avoids first-pass metabolism, which can enhance bioavailability compared to traditional delivery methods