GLP-1 receptor activation also decreases intestinal motility and delays gastric emptying
Importantly, estrogen has also been shown to enhance memory function, specifically in hippocampal mechanisms [51]
While the mechanism by which GSTO1 interacts with these genes and pathways remains to be fully characterized, GSTO1 catalytic activity appears to be important for this regulation
It is not yet well-understood how these bacteria can exert these benefits, but documented mechanisms of action include antimicrobial activity against major gastrointestinal 171 and urogenital pathogens 172 , barrier-promoting effects at the gut epithelium 173 and other mucosa 174 , immunomodulatory effects by stimulating host antimicrobial compounds such as - defensins 175 and modulating the secretion of cytokines such as IL-10, IL-6, IL-1b, IL-2, TNF-, and impacting different cell types such as intestinal epithelial cells, dendritic cells, macrophages and regulatory T cells 176,177,178
Dynamic Light Scattering provides data on particle size distribution