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Therapeutic approaches in the improvement of cognitive performance in Down syndrome: Past, present, and future

Abstract Background/Objectives Glucagon-like peptide-1 receptor agonist medications (GLP-1s) are effective for weight loss, but when people discontinue them, they tend to regain weight

J Clin Endocrinol Metab 2005;90:493-500

The main downside is using sucralose as the sweetener, which some studies suggest could have adverse long-term health effects

Ristoff E, Hebert C, Njalsson R, et al (2002) Glutathione synthetase deficiency: Is -glutamylcysteine accumulation a way to cope with oxidative stress in cells with insufficient levels of glutathione