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If you have obesity-related conditionssuch as type 2 diabetes, hypertension, or sleep apneastarting now with an approved injectable GLP-1 may make sense

Think of it as preventive medicine: You're not waiting for problems to arise

Albiglutide comprises two copies of GLP-1 fused as tandem repeats to the N terminus of albumin [3], while dulaglutide is a recombinant fusion protein consisting of two GLP-1 peptides covalently linked to a human IgG4-Fc heavy-chain variant [3]

Subcutaneous and intraperitoneal routes give shorter circulating windows, with the compound clearing primarily through proteolytic degradation outside the GI tract rather than through renal or hepatic elimination as a single molecule

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