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Thus, the use of peripheral blood eosinophils to guide therapy to anti-IL-5 biologics may not be as ideal as sputum eosinophils

For immunolabeling, cells were incubated with anti-mouse CD16/32 (eBioscience Ref 16-0161-85, 1:100) for 15 min to block Fc receptors

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While the disruption of epithelial integrity and persistent inflammation are well-established contributors to disease pathogenesis, recent findings indicate that ferroptosis serves as a central regulatory node in intestinal epithelial cell (IEC) injury and immune activation (166, 167)

Eli Lilly will likely set a launch price in the $1,000$1,500 monthly range based on competitive positioning