NTS GLP-1R neurons, sensitive to nutritive stimuli, induced satiety without aversion, whereas AP GLP-1R neurons elicited strong nausea-like behavior in mice
Preliminary human studies suggest potential benefits in improving biological markers of aging
In partnership with BioMed X, the company is working on optimising the bioavailability of semaglutide and similar peptides, aiming to enhance absorption and targeted release in the lower small intestine, potentially increasing efficacy and adherence for oral obesity treatments.
At more modest levels, research (in older men) has shown HGH may have a positive impact on muscle tone, strength, and anaerobic exercise capacity (which can contribute to fat loss and muscle gain)
Thiazolidinediones have been associated with a reduced risk of certain cancers, although concerns over their safety continue to be debated