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These cardiovascular benefits likely reflect both the direct vascular effects of weight loss and potential direct receptor-mediated effects on vascular function
41:e4-e5 [PubMed: 29133344] 231
Many plans require prior authorization with documentation of: BMI criteria matching FDA-approved indications For OSA-specific coverage (with tirzepatide), documented OSA diagnosis with polysomnography or home sleep testing showing AHI 15 Participation in lifestyle modification programs Absence of contraindications Even with approval, coverage may include quantity limits, step therapy requirements (trying other weight loss medications first), or annual spending caps
Hyldstrup, L., Andersen, T., McNair, P., Breum, L
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