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The two-year window before approval is clinically useful: initiating supervised GLP-1 or dual-agonist therapy now addresses metabolic risk that is accumulating today

It can be caused by alcohol consumption (alcoholic fatty liver disease) or non-alcoholic factors such as obesity, high cholesterol, and diabetes (non-alcoholic fatty liver disease)

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Initially developed as diabetes medications, their profound benefits for the heart and kidneys have completely reshaped our approach to managing cardiometabolic disease

"There are additional complex metabolites that others are looking at, so we're potentially opening a whole new interest into how cancer cells acquire nutrients and how to block that activity