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Information on trials currently recruiting in the UK can be found via the NIHR Be Part of Research platform (bepartofresearch.nihr.ac.uk) or ClinicalTrials.gov

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In particular, incomplete retrieval of grey literature and insufficient documentation of study-exclusion decisions could lead to overestimation of benefits or underdetection of harms, while the infrequent propagation of primary-study bias into meta-analytic models reduces confidence in the magnitude of pooled effects

The American Diabetes Association emphasizes in its Standards of Care that medication adherence is a critical determinant of treatment success, and choosing a convenient, memorable time significantly enhances long-term compliance with tirzepatide therapy

If your FTO genotype suggests metabolic inflexibility, you may prioritize intensive behavioral support during any treatment break