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It can reduce the noise around food and create momentum that finally feels sustainable

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For some, taking it first thing in the morning with breakfast is the easiest way to ensure that youre getting your daily dose

The absence of controlled trials means the true benefit-risk profile remains inadequately defined

PIONEER 3 study design 1,4 In a double-blind, double-dummy trial with a primary endpoint of mean change in A1C from baseline to 26 weeks, 1864 adult patients with type 2 diabetes on metformin alone or metformin with a sulfonylurea were randomized to RYBELSUS 3 mg (n=466), RYBELSUS 7 mg (n=465), RYBELSUS 14 mg (n=465), or Januvia 100 mg (n=467), all once daily