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10.1073/pnas.0702018104 27 NoveroA

The Food and Drug Administration warned last month about reports that consumers developed severe infections and skin deformities after they got unauthorized shots touted to dissolve fat at med spas across the country

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Vitamin B12 deficiency may lead to anaemia as a result of disrupted DNA, leading to the production of mutant cells called megaloblasts

Despite the short plasma half-life, downstream biological effects in tissue persist substantially longer, consistent with a signaling cascade rather than direct dose-response activity