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Based on available intake data, adult consumers are unlikely to exceed the TUL, except for regular users of food supplements containing high daily doses of selenium [93]

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Tumor heterogeneity further complicates this landscape, as the extent of GSH dependency varies across tumor types, metabolic states, and microenvironments, with poorly defined consequences for therapeutic response

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The chemical reactions of metabolism are organized into metabolic pathways, in which one chemical is transformed through a series of steps into another chemical, each step being facilitated by a specific enzyme