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Recently, ketamine and psilocybin gained attention as potential sustained antidepressants

F., Olson, G

Receptor activation can be maintained for the duration of the experiment without dosing complexity

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Back McLean, BA, Wong, CK, Campbell, JE, et al (2021) 'Revisiting the complexity of GLP-1 action from sites of synthesis to receptor activation', Endocrine Reviews , 42/2, 101-32