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Understanding the physiology of natural GLP-1 provides essential context for appreciating why pharmaceutical modifications were necessary to harness its therapeutic potential for chronic disease management, particularly in type 2 diabetes and obesity treatment
Perturbations in the RAAS are implicated in the progression of cardiovascular dysfunction and nephropathy associated with poorly controlled T2DM [266]
The other authors declare no conflicts of interest
The number appears to derive partly from the saturation dose concept discussed next, and partly from convention propagated across forums and vendor literature until repetition lent it a false air of authority
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