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Lamont BJ, Li Y, Kwan E, Brown TJ, Gaisano H, and Drucker DJ

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SHU-9119 is the same MT-II scaffold with D-2-naphthylalanine substituted at position 7, a single change that converts it from a full agonist into an MC3R and MC4R antagonist while remaining an agonist at MC1R and MC5R

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Subsequent studies by Hadley & Dorr (2006) reviewed the extensive body of work on melanotropic peptides, documenting MT-2's central role in pigmentation research