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Acknowledgements none Funding This work was supported by the National Natural Science Foundation of China (No

Model building The maximal effect (E max ) model built up via non-linear mixed-effect modeling (NONMEM, edition 7, ICON Development Solutions, Ellicott City, MD, United States) was used for analysis

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You Might Be Low on B Vitamins If youre pregnant, caring for young kids, or just simply running on empty, theres a real chance your body is low on the nutrients it needs to keep you going

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