Ca 2+ is a master regulator of eryptosis, mediating the Gardos effect-associated RBC dehydration and reduction of cell volume (cell shrinkage), calpain activation-mediated cytoskeleton remodeling (membrane blebbing), and PS externalization, which are major hallmarks of eryptosis
29 Complex I produces most of the superoxide that is generated by mammalian mitochondria in vitro
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pylori infection, regulation of TNF- transcription depends on alternative activation of NF-B through the phosphorylation of the p65 subunit RELA at Ser-536 that does not involve NFKBIA degradation (56)
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