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This typically involves: Intrinsic factor antibodies (highly specific for pernicious anaemia, though sensitivity is only 50%) [12] [28] Gastric parietal cell antibodies (more sensitive but less specific) Coeliac serology if malabsorption is suspected Consideration of upper gastrointestinal endoscopy in selected cases, particularly with autoimmune gastritis/pernicious anaemia NICE guidance emphasises that treatment should not be delayed whilst awaiting antibody results if clinical features strongly suggest deficiency, as irreversible neurological damage can occur
FDA issued a warning letter identifying 5-Amino-1MQ as ineligible for 503B compounding exemptions
For those, generally, we use Vbeam, which is a pulse-dyed laser that is specifically attracted to red pigment
How to Test: The Right Investigations Most routine blood panels measure serum B12, which gives a useful starting point