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They fall instead under the general remit of the Human Medicines Regulations 2012, which is why unlicensed injectable preparations cannot lawfully be supplied for human administration regardless of "research use only" labelling [3][4]

Inflammatory mediators are released within seconds due to the overproduction of IgE which binds to mast cells and allergens

[4] [5] Patients considering these treatments should understand that they are not a substitute for lifestyle modification or evidence-based weight management strategies endorsed by NICE

10.1016/j.phrs.2018.07.015 6 ArifE.SolankiA