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Melrose et al ., 1990)

It is also important for general vitality as it is involved in energy metabolism

In insulin resistance, cells stop responding properly to insulin

445 Immunotherapeutic treatments have shown significant efficacy in TNBCs due to tumor immune infiltration, neoantigens caused by mutational burden and higher genomic instability, and high levels of immune markers such as PD-L1 and programmed cell death 1 (PD-1)

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