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Endocrinology 155 , 30883097
Faza I bada bezpieczestwo na maej grupie zdrowych ochotnikw czy substancja jest tolerowana, jakie s skutki uboczne, w jakich dawkach staje si toksyczna
(Migraines are considered chronic when someone has a headache on 15 or more days a month for at least three months.) The researchers divided the participants into two groups: Those who started taking a GLP-1 medication for another condition (such as type 2 diabetes or obesity) within a year of being diagnosed with chronic migraines, and those who started taking topiramate (a prescription medication used to prevent migraine headaches) during the same period
This might have to do with its capacity to prevent the PI3K-Akt-mTOR and Extracellular Signal-Regulated Kinase (ERK) pathways, which enhances suppressive functioning and increases the number of Treg cells (278)
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