Garlic organosulfur compounds were shown to exert their immunomodulatory activity via inhibition of the transcription factor NF-B, leading to decreased levels of pro-inflammatory cytokines, such as TNF-, IL-1, IL-6, MCP-1, and IL-12 ( 2+ from proteins in murine EL-4 T-cells, possibly due to S -thioallylation of Zn 2+ coordinating Cys thiolates ( 2+ levels due to inactivation of host proteins by S -thioallylation
& Eijkelkamp, N
[DOI] [PMC free article] [PubMed] [Google Scholar] 73.Yang L., Lin I.H., Lin L.C., Dalley J.W., Tsai T.H
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