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Claiming the patch lasts 20x longer than injections with no data or plausible mechanism of action to back it up is highly suspect

Abstract Glucagon-like peptide 1 (GLP-1)-based therapies, such as semaglutide and tirzepatide, represent highly effective treatment options for people with type 2 diabetes and obesity, enabling effective control of glucose and weight loss, while reducing cardiovascular and renal morbidity and mortality

2004 Nov;1033:117-31.Comparison of the effects of L-carnitine and acetyl-L-carnitine on carnitine levels, ambulatory activity, and oxidative stress biomarkers in the brain of old rats

No formal a priori sample size calculation was performed

As the loss of POLRMT results in severe mitochondrial dysfunction in cardiac muscle 70 , a similar mitochondrial dysfunction should occur in beta-cells with the loss or dysfunction of POLRMT, resulting in insulin resistance and diabetes mellitus