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Additional signaling processes may involve calcium flux, kinase activation, and transcriptional changes that alter metabolic enzyme expression and neuroendocrine signaling networks
Furthermore, advances in our understanding of cerebellar development, genetics, anatomy, and electrophysiological properties provide an ever-growing number of ideas towards which one can be enthusiastic about, especially given the range of motor and non-motor functions that are now attributed to normal cerebellar function
Dosis-respuesta : curva tipo campana en algunos modelos, con dosis intermedias produciendo efectos ptimos y dosis muy altas atenuando la respuesta (fenmeno de hormesis molecular descrito por Sikiric et al.)
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