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found that liraglutide, an GLP-1R agonists, reduces the activated microglia load in the cortex and dentate gyrus region of hippocampus, and the activated astrocyte load in the cortex

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The phase 3, double-blind, placebo-controlled STEP TEENS trial demonstrated the efficacy and safety of semaglutide 2.4 mg once weekly for weight management among adolescents with obesity