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Once inside the mitochondria, these fatty acids undergo beta-oxidation, a metabolic pathway that breaks them down into acetyl-CoA, which then enters the Krebs cycle to generate adenosine triphosphate (ATP), the bodys main energy currency

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JAMA Surgery study of 1,046 patients identified independent risk factors for food retention with GLP-1 RA use (odds ratio 9.19, 95% confidence interval 2.7330.8), with tirzepatide demonstrating the strongest association amongst available agents [33]

muciniphila compared to patients that succumbed to the disease