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The population who switched were made up of a higher percentage of people in the 45-64 age range, female, white, not Hispanic or Latino, those with overweight/obesity, T2D, and those who initiated treatment before 2021

Intestinal bacterial colonization induces mutualistic regulatory T cell responses

This is particularly relevant for users who experienced little to no bloating at lower doses but find the transition to the 1.0mg or 1.7mg level overwhelming