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Twice-daily dosing is used in some early-phase research protocols to maintain more consistent receptor activation during the initial neuroplasticity induction period, but this approach increases total daily exposure and may elevate the risk of off-target effects

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The peptide also attracts immune cells to wound sites, stimulates nerve growth, and promotes angiogenesis

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Malutan AM, Drugan T, Costin N, Ciortea R, Bucuri C, Rada MP, Mihu D (2015) Pro-inflammatory cytokines for evaluation of inflammatory status in endometriosis