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Furthermore, three studies showed that SGLT-2 inhibitors reduced diabetes mellitus (DM) onset, though statistical significance was not achieved (p-value = 0.08, SMD: -2.21, CI: [-5.11, 0.69])

Liver disease and cancer

(2005) Ghrelin regulates mitochondrial-lipid metabolism gene expression and tissue fat distribution in liver and skeletal muscle

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