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DJ-1 associates with lipid rafts by palmitoylation and regulates lipid rafts-dependent endocytosis in astrocytes

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In chronic tinnitus and neurodegenerative diseases, dysfunction of the Nrf2/ARE pathway has been increasingly recognized as a critical factor contributing to the collapse of endogenous antioxidant defenses (Scuto et al., 2020

Hence, glutamine is a key structural building block in the biosynthesis of proteins, nucleotides, non-essential amino acids and polyamines to support biomass accumulation and rapid rates of proliferation

A casecontrol study that included 67 PD patients compared to 24 healthy controls showed that plasma levels of -synuclein, NLRP3 inflammasome, caspase-1, and IL-1 increased in PD patients compared to healthy patients controls (Fan et al