Each compound, with the exception of 1.65 , showed no cytotoxicity up to 3.25 mmolL 1 , and there was mostly over 100% cell viability on Caco-2, Fibroblast, and HT29-MTX-E12 cells at each tested concentration (as shown in Table 7)
Other compounds studied for related recovery mechanisms include BPC-157, TB-500, and the BPC-157/TB-500 blend
These range from visual stimulation experiments that allow us to tap into the specific sets of retinal ganglion cells that are most vulnerable early in the disease, to the evolution of new imaging techniques, largely thanks to Alf Dubra and Vivek Srinivasans work in those areas, and the ability to image retinal ganglion cells and their component parts like their axons which degenerate very early in glaucoma
doi: 10.2337/db14-0621 81 DHertogWOverberghLLageKFerreiraGBMarisMGysemansCet al
These findings support the use of microbiome-targeted interventions early in life or illness to potentially mitigate progression of severe psychiatric conditions