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Phase 2b VESPER-1 and VESPER-3 completed (2025)

Weeks 1-4: 2.5 mg once weekly Weeks 58 : 5 mg once weekly Weeks 912 : 7.5 mg once weekly if you can tolerate the previous dosage and further glycemic control is needed Weeks 1316 : 10 mg once weekly, if you have still not reached your target blood sugar levels Weeks 1720 : 12.5 mg once weekly, if needed Week 20 and onwards : 15 mg once weekly, which is the maximum dosage of Mounjaro If you experience side effects, your doctor may delay dosage escalation for the next 4 weeks or lower the dosage of Mounajro

Daily-life factors can also contribute

What You'll Need Required Supplies Semaglutide vial (lyophilized powder, typically 3mg, 5mg, or 10mg) Bacteriostatic water (BAC water): contains 0.9% benzyl alcohol as preservative Insulin syringes (U-100, 0.5mL or 1mL with fine gauge needle) Alcohol swabs (70% isopropyl alcohol) Optional but Recommended Larger mixing syringe (3mL) for adding BAC water Sharps container for safe needle disposal Clean workspace with good lighting Vial labels to mark reconstitution date and concentration Do NOT use: Sterile water or saline without preservative

Flares trigger less easily