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Finally, experiments showed that MgIG suppressed the production of pro-inflammatory lipid mediators generated through the arachidonic acid metabolic pathway, including prostaglandin E 2 (PGE 2 ), prostacyclin (PGI 2 ), thromboxane B 2 (TXB 2 ), and leukotriene B 4 (LTB 4 ) (Xie et al., 2015)