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A previous study reported that anti-depressant therapy can increase the level of BDNF and subsequently boost neurogenesis, attenuate neuronal apoptosis in the depressive brain, and ultimately improve depressive mood (Sahay and Hen, 2007)

If you're treated for it and take your B12 supplements daily, you can live a normal lifespan

(2019) 11:e4715

Analysis of the GSTF8-L and GSTF8-S proteins demonstrated that GSTF8-L is solely targeted to plastids, whereas GSTF8-S is cytoplasmic (Thatcher et al., 2007)

Summary: There is a lot of conflicting advice around the use of GLP-1 medications before surgery, which can be overwhelming