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Studies with Eaat3-knockout mice have demonstrated that the absence of Eaat3 leads to reduced glutathione content in neurons and early onset brain aging due to oxidative stress

Both glucose and sodium ions bind to the cotransport protein, with the Na + electrochemical gradient, maintained by the basolateral sodiumpotassium adenosine triphosphatase, driving glucose uptake across the luminal membrane ( Figure 1 )

As cheaper versions become widely available, adherence and continuity of care could become major concerns

Therefore, if clinical research confirms the involvement of NETs in ECMO-related acute brain injury, it would become a critical target for preventing complications associated with brain damage

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