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Previous meta-analyses on the effects of GLP-1 agonists on glycemic parameters and weight reduction showed contradicting results and are limited by the small number of included studies (31), including studies with overlap (published by the same authors), and high heterogeneity (32, 33)

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First and foremost, individuals should consult with a healthcare professional, particularly if they have pre-existing medical conditions or are taking other medications

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Additionally, by activating the GCGR, Retatrutide may influence glucose production in the liver, providing a dual approach to glucose regulation