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Baseline liver enzyme assessment is reasonable for patients with: Pre-existing liver disease or elevated baseline transaminases Metabolic syndrome or clinical features suggesting MASLD Concurrent use of other potentially hepatotoxic medications Obesity (BMI 30 kg/m) with additional metabolic risk factors History of excessive alcohol consumption For patients with abnormal baseline liver enzymes, periodic monitoring every 3-6 months during the first year of therapy allows clinicians to assess treatment response and detect any unexpected changes
However, these symptoms can have many causes, making professional evaluation important
199 SchelfhoutV.LouisR.LenzW.HeyrmanR.PauwelsR.JoosG
Ayalaxomayajula SP, Kompella UB
Seventy-two hours of treatment with menadione (20 M) was carried out as a positive control
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